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Bcl-XL An anti-cancer peptide inhibiting Bcl-XL and a method for screening an anti-cancer agent
Bcl-XL An anti-cancer peptide inhibiting Bcl-XL and a method for screening an anti-cancer agent
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机译:Bcl-XL抑制Bcl-XL的抗癌肽及抗癌剂的筛选方法
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摘要
The present invention relates to a peptide for preventing or treating cancer capable of inducing cell death in a transcription-independent manner, a pharmaceutical composition comprising the same, and a screening method using the same. The peptide of the present invention can induce cell death by forming a complex with Bcl-X L , which can be used for cancer treatment, while screening an anticancer agent using the structure of the complex.
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机译:本发明涉及用于预防或治疗能够以转录非依赖性方式诱导细胞死亡的癌症的肽,包含该肽的药物组合物以及使用该肽的筛选方法。本发明的肽通过与Bcl-X L Sub>形成复合物可诱导细胞死亡,所述复合物可用于癌症治疗,同时使用该复合物的结构筛选抗癌剂。
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