LysCPD2 Thermal stable endolysin LysCPD2 with lytic activity against Clostridium perfringens

摘要

The present invention relates to a thermal stable endolysin LysCPD2 with lytic activity against Clostridium perfringens. Newly isolated endolysin LysCPD2 in the present invention shows a specific lytic activity against strains of the genus Bacillus and strains of the genus Clostridium, one of the causes of food poisoning and, in particular, exhibits stable antibacterial activity even when heat is applied. Therefore, endolysin of the present invention can be used for treating diseases caused by the infection of Clostridium perfringens, and, as a biological control agent, can contribute to the reduction of diseases in livestock and poultry caused by Clostridium perfringens, and also can improve the consumption stability of livestock and poultry through the development of a novel concept of controlling antibiotic resistant bacteria.