SMAC 6- 6-Alkynyl pyridines as SMAC mimetics

摘要

The present invention provides for the treatment and / or treatment of 5-alkynyl-pyridine of formula (I) for use as a SMAC mimetic, pharmaceutical compositions containing it, and related symptoms such as diseases and cancers characterized by excessive or abnormal cell proliferation Its use as a medicament to prevent: Wherein groups R ¹ to R ⁵ have the meanings given in the claims and the specification.