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Compositions of orally disintegrating tablets containing corticosteroids for the treatment of eosinophilic esophagitis

机译:包含皮质类固醇的口腔崩解片的组合物,用于治疗嗜酸性粒细胞性食管炎

摘要

The present invention is directed to orally administered compositions of topically acting corticosteroids for the treatment of inflammation of the gastrointestinal tracts such as eosinophilic esophagitis. The present invention also provides a method for treating conditions associated with inflammation of the gastrointestinal tract in an individual. The method comprises administering to an individual in need thereof a pharmaceutical composition of the present invention as orally disintegrating tablets comprising a topically active corticosteroid adsorbed onto a pharmaceutically acceptable carrier such as silicified microcrystalline cellulose.
机译:本发明涉及局部给药的皮质类固醇的口服组合物,用于治疗胃肠道的炎症,例如嗜酸性食管炎。本发明还提供了一种治疗个体中与胃肠道炎症相关的病症的方法。该方法包括将本发明的药物组合物作为口腔崩解片给予包含有需要的个体,该片剂包含吸附在药学上可接受的载体例如硅化的微晶纤维素上的局部活性皮质类固醇。

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