首页> 外国专利> METHOD OF INTERSTITIAL, HIGH-POWER BRACYTHERAPY OF LOCAL DISTRIBUTED TUMOR TUMORS WITH LATERAL INVASION IN THE SMALL PELVIS WALL

METHOD OF INTERSTITIAL, HIGH-POWER BRACYTHERAPY OF LOCAL DISTRIBUTED TUMOR TUMORS WITH LATERAL INVASION IN THE SMALL PELVIS WALL

机译:小骨盆壁局灶性局部肿瘤伴侧向性间质性高通气治疗的方法

摘要

FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to oncology, radiation therapy and surgery. Perform high-power brachytherapy with 192Ir radiation source on afterloading system. After the surgical intervention of the pelvic organs, introducers of 6Fr diameter are installed on a tumor bed intraoperatively under vision control. It is brought out through separate punctures on anterior abdominal wall or perineum and sutures are fixed to patient's skin. Spasemaker or an expander is placed in a small pelvis cavity in the irradiation field, a laparotomic wound is closed, and after stabilization of the patient's condition on 1st-8th day, the target is delineated and the radiation field is planned taking into account the size, localization and risk organs. Position of the introducers is taken as a coordinate system x, y, z, after which high-power brachytherapy is performed with a radiation source of 192Ir in a single boost dose of 5 Gy once a day daily for five days on the afterloading system.EFFECT: method provides higher clinical effectiveness in locally advanced pelvic tumors with lateral invasion, the method is well tolerated, accompanied by moderate, recoverable toxic reactions.1 cl, 5 dwg, 1 tbl, 1 ex
机译:领域:药物。物质:发明涉及药物,即肿瘤学,放射疗法和外科手术。在后装系统上使用192Ir辐射源进行大功率近距离放射治疗。在盆腔器官的外科手术干预之后,在视觉控制下术中在肿瘤床上安装直径为6Fr的导引器。通过前腹壁或会阴的单独穿刺将其带出,并将缝合线固定在患者的皮肤上。将Spasemaker或扩展器放在照射区域的小骨盆腔中,闭合腹腔伤口,并在患者的病情稳定后的第1至第8天,确定目标,并根据大小规划辐射区域,本地化和风险机构。导引器的位置取作坐标系x,y,z,之后每天在后加载系统上每天一次以5 Gy的单次增强剂量用192Ir放射源进行大功率近距离放射治疗。效果:该方法在局部侵袭性局部盆腔肿瘤中具有较高的临床疗效,该方法耐受性良好,伴有中度,可恢复的毒性反应。1cl,5 dwg,1 tbl,1 ex

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