VIRUS STRAIN FOR PRODUCING VACCINE DRUGS AGAINST HEMORRHAGIC FEVER WITH RENAL SYNDROME (OPTIONS)

摘要

FIELD: biotechnology.;SUBSTANCE: invention is a DOB-SOCHI/VERO strain of the Dobrava-Belgrade orthohantavirus virus (Hantaviridae family, Bunyavirales order), deposited under No. 1282 in the State collection of viruses (N. F. Gamaleya Federal Research Center for Epidemiology & Microbiology of the Ministry of Health of Russia), adapted for reproduction in Vero grass monkey kidney cell culture, intended for the manufacture of vaccine preparations for the specific prevention of hemorrhagic fever with renal syndrome, as well as strain HTN-P88/VERO of the Hantaan orthohantavirus virus (Hantaviridae family, Bunyavirales order), deposited under No. 1283 in the State collection of viruses (N. F. Gamaleya Federal Research Center for Epidemiology & Microbiology of the Ministry of Health of Russia), adapted for reproduction in Vero grass monkey kidney cell culture, intended for the manufacture of vaccine preparations for the specific prevention of hemorrhagic fever with renal syndrome.;EFFECT: virus strains is proposed for the prevention of hemorrhagic fever with renal syndrome.;2 cl, 1 tbl, 1 ex