A method of identifying naive CD8 + T cells in a human-derived sample comprising analyzing a modification such as the methylation status of at least one CpG position in the human endosialin gene region (CD248), preferably the analyzed gene region according to SEQ ID No. 1 is positioned, with a missing modification, such as demethylation or lack of methylation of the gene region is indicative of a naive CD8 + T cell compared to a non-naive CD8 + T cell.
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机译:一种鉴定人源样品中的幼稚CD8 + T细胞的方法,包括分析修饰,例如人内皮唾液酸蛋白基因区域(CD248)中至少一个CpG位置的甲基化状态,优选根据SEQ ID No.相对于非天然CD8 + T细胞,.1定位,具有缺失的修饰,例如基因区域的去甲基化或缺乏甲基化,指示天然CD8 + T细胞。
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