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HIV IMMUNE STIMULATING COMPOSITIONS COMPRISING RECOMBINANTLY EXPRESSED PILI ON BACTERIA AND METHODS RELATED THERETO
HIV IMMUNE STIMULATING COMPOSITIONS COMPRISING RECOMBINANTLY EXPRESSED PILI ON BACTERIA AND METHODS RELATED THERETO
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机译:包含重组表达的小肠细菌的HIV免疫刺激组合物及其相关方法
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摘要
This disclosure relates to recombinant bacteria, e.g. L. lactis, expressing heterologous pili containing human immunodeficiency virus (HIV) antigens. In certain embodiments, the recombinant bacteria are administered in combination with other HIV antigens, nucleic acids encoding HIV antigens, recombinant virus encoding HIV antigens, anti-viral agents and/or adjuvants in an effective amount to elicit a mucosal immune response against HIV.
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