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COMPOSITIONS OF BUPRENORPHINE AND MU-OPIOID RECEPTOR ANTAGONISTS
COMPOSITIONS OF BUPRENORPHINE AND MU-OPIOID RECEPTOR ANTAGONISTS
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机译:丁丙诺啡和阿片受体拮抗剂的组成
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摘要
The invention relates to a composition comprising buprenorphine and a µ opioid receptor antagonist, wherein the composition is characterized by an Agonist Antagonist Activity Index (AAnAI) of between about 0.7 and about 2.2; wherein; AAnAI = / EC 50 C max BUP / EC 50 C max ANTAGONIST .
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机译:本发明涉及一种包含丁丙诺啡和μ阿片样物质受体拮抗剂的组合物,其中该组合物的特征在于激动剂拮抗活性指数(AAnAI)为约0.7至约2.2。其中; AAnAI = / EC 50 C max BUP / EC 50 C max ANTAGONIST。
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