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2-(3-PYRIDINYL)-1H-BENZIMIDAZOLE DERIVATIVE COMPOUND AND MEDICINE CONTAINING SAME

机译:2-(3-吡啶基)-1H-苯并咪唑衍生物化合物和相同的药物

摘要

Provided is a compound represented by general formula (1) or a salt thereof as well as a medicine containing the compound or the salt. (In the formula, R 1 represents a hydrogen atom or CO 2 R a ; R 2 represents a hydrogen atom, a halogen atom, or CO 2 R a ; R 3 represents a hydrogen atom or a C1-10 hydroxyalkyl group; R 4 represents a hydrogen atom, a hydroxy group, or a C1-10 alkoxy group; R 5 represents a C1-5 chain alkyl group in which the hydrogen atoms are optionally substituted with halogen atoms, a C3-5 cyclic alkyl group in which the hydrogen atoms are optionally substituted with halogen atoms, a C1-5 hydroxyalkyl group, or an o-, p-, or m-halobenzyl group; A represents CH or a nitrogen atom; X 1 and X 3 independently represent hydrogen atoms or halogen atoms; X 2 represents a hydrogen atom, a halogen atom, or a nitrile group; at least one of X 1 , X 2 , and X 3 represents a halogen atom; and R a independently represents a C1-10 alkyl group.)
机译:提供通式(1)表示的化合物或其盐以及含有该化合物或盐的药物。 (式中,R 1表示氢原子或CO 2 R a; R 2表示氢原子,卤原子或CO 2 R a; R 3表示氢原子或C1-10羟烷基; R 4 R 5表示氢原子,羟基或C 1-10烷氧基; R 5表示其中氢原子任选被卤素原子取代的C 1-5链烷基,其中氢为C 3-5环烷基原子任选地被卤素原子,C 1-5羟烷基或邻,对或间卤苄基取代; A代表CH或氮原子; X 1和X 3独立地代表氢原子或卤素原子; X 2表示氢原子,卤素原子或腈基; X 1,X 2和X 3中的至少一个表示卤素原子;并且R a独立地表示C1-10烷基。

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