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IMMUNOMODULATORY CELLS AND IL-25 TO UPREGULATE THE EXPRESSION OF PD-L1
IMMUNOMODULATORY CELLS AND IL-25 TO UPREGULATE THE EXPRESSION OF PD-L1
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机译:免疫调节细胞和IL-25上调PD-L1的表达
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摘要
The present application provides a method of upregulating an expression of immumodulatory cells in vitro comprising treating the immumodulatory cells with IL-25 to increase an expression of PD-L1. The present application also provides a method for treatment of immune disorders by the aforementioned methods. The present application also provides a method to suppress an expression of immumodulatory cells comprising suppressing an expression of PD-L1. The immumodulatory cells can be human monocytes or hMSCs. The present application further provides a method for treatment of immune-evasive diseases by using the aforementioned method to suppress an expression of immumodulatory cells.
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