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Topical pharmaceutical and medical device preparations containing combinations of sucralfate, hyaluronic acid, arginine and a natural moisturizing agent

机译:包含硫糖铝,透明质酸,精氨酸和天然保湿剂组合的局部药物和医疗器械制剂

摘要

The present application relates to topical preparations containing, based on the total weight of the composition: (A) 0.05-5.0 wt% sucralfate (B) 0.05-5.0 wt% hyaluronic acid or hyaluronate salt thereof (C) 0.05-5.0 wt% of a natural moisturizing agent (e.g. natural yogurt or yogurt derivatives or milk fermentation products or honey or honey products or mixtures thereof) (D) 0.05-5.0 wt% L-Arginine, (E) 80.0-98.0 wt% water And (F) 1.0-15.0 wt% of a carrier or vehicle, other than water. These preparations are stable and show rheological properties comparable to the ones of the compositions that are already in the market for similar uses, while the healing time is shorter and / or the clearance of skin lesions is of a higher degree and therefore, these combinations are useful in treating diseases or disorders of the skin or the oral cavity.
机译:本申请涉及局部用制剂,其基于组合物的总重量包含:(A)0.05-5.0 wt%硫糖铝(B)0.05-5.0重量%的透明质酸或其透明质酸盐(C)0.05-5.0 wt%的天然保湿剂(例如天然酸奶或酸奶衍生物或牛奶发酵产品或蜂蜜或蜂蜜产品或其混合物)(D)0.05-5.0 wt%的L-精氨酸,(E)80.0-98.0 wt%的水和(F)水以外的载体或媒介物的1.0-15.0 wt%。这些制剂是稳定的,并具有与市场上类似用途的组合物相当的流变性能,同时愈合时间更短和/或皮肤损伤的清除程度更高,因此,这些组合是用于治疗皮肤或口腔疾病或病症。

著录项

  • 公开/公告号EP2810641B1

    专利类型

  • 公开/公告日2020-02-26

    原文格式PDF

  • 申请/专利号EP20140386014

  • 发明设计人 TSETI IOULIA;

    申请日2014-05-30

  • 分类号A61K9;A61K31/198;A61K8;A61K31/7024;A61K31/728;

  • 国家 EP

  • 入库时间 2022-08-21 11:41:54

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