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METHOD AND SYSTEM FOR ESTIMATING A GENDER OF A FOETUS OF A PREGNANT FEMALE
METHOD AND SYSTEM FOR ESTIMATING A GENDER OF A FOETUS OF A PREGNANT FEMALE
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机译:估计孕妇的胎儿性别的方法和系统
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摘要
A method for estimating a gender of a foetus of a pregnant female, said method comprising measuring allele presences (Dx) for a first plurality of genetic markers of the X-chromosome and allele presences (DR) for a second plurality of genetic markers of at least one reference chromosome, different from the X and Y chromosome, in a sample of cell-free DNA from a pregnant female; based on said measured allele presences for said first plurality, determining a first fraction thereof which is associated with purely homozygous genetic markers; based on said measured allele presences for said second plurality, determining a second fraction thereof which is associated with purely homozygous genetic markers; and estimating a gender of said foetus based on said first and second fraction.
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