ANTI-CDH3 ANTIBODY HAVING HIGH INTERNALIZATION CAPACITY

摘要

It is an object of the present disclosure to provide an anti-cadherin antibody having a high internalization capacity and provide an anti-cadherin antibody-drug conjugate that effectively kills cadherin-expressing cancer cells with the use of such antibody. The present disclosure provides an anti-cadherin antibody which recognizes a cadherin domain 1 (EC1) of cadherin and exhibits a high internalization capacity.