首页> 外国专利> AN ATOMIC FORCE MICROSCOPE INTEGRATED WITH A MULTIPLE DEGREES-OF-FREEDOM MAGNETIC ACTUATOR

AN ATOMIC FORCE MICROSCOPE INTEGRATED WITH A MULTIPLE DEGREES-OF-FREEDOM MAGNETIC ACTUATOR

机译:集成了多个自由度磁致动器的原子力显微镜

摘要

The present invention relates to a biomolecular measurement system (1), which enables to measure the intermolecular forces arising from the interaction between two biomolecules or the intramolecular forces within a single biomolecule by using an atomic force microscope (AFM). In the present invention, the cantilever (2) is moved only when the actuator (4) moves the magnetic nanowire (3) and thus moves the molecule attached to the end of the magnetic nanowire (3). Since the cantilever (2) is not moved, fluctuation and disturbance is not created in the liquid containing the biomolecules. Thus, the measurements are made more accurately and with higher resolution. Additionally, by means of the actuator (4), the biomolecules are enabled to be moved upon exertion of magnetic force at any coordinate on x, y and z axes on the nanowire (3), or exertion of torque on two axes.
机译:本发明涉及一种生物分子测量系统(1),其能够通过使用原子力显微镜(AFM)来测量由两个生物分子之间的相互作用或单个生物分子内的分子内力引起的分子间力。在本发明中,仅当致动器(4)移动磁性纳米线(3)并因此移动附着于磁性纳米线(3)末端的分子时,悬臂(2)才移动。由于悬臂(2)不移动,所以在含有生物分子的液体中不会产生波动和干扰。因此,可以更准确,更高分辨率地进行测量。另外,借助于致动器(4),当在纳米线(3)的x,y和z轴上的任何坐标上施加磁力或在两个轴上施加扭矩时,生物分子就能够移动。

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