首页> 外国专利> DISUBTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES AS INHIBITORS OF MONOAMINE OXIDASE B FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES

DISUBTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES AS INHIBITORS OF MONOAMINE OXIDASE B FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES

机译:二氧化氮,吡咯烷二酮,哌啶和氮杂作为单胺氧化酶B抑制剂可治疗神经退行性疾病

摘要

This invention relates to new inhibitors of MAO-Bwith the general formula I, where substituents are described in patent description. Compounds can be in the form of pure enantiomers or as racemic mixtures, or in the form of pharmaceutically acceptable salts. The present invention relates to the use of these inhibitors for the alleviation of symptoms and treatment of acute and chronic neurological disorders, cognitive and neurodegenerative diseases.
机译:本发明涉及具有通式I的MAO-B的新抑制剂,其中在专利说明书中描述了取代基。化合物可以是纯对映体形式或外消旋混合物形式,或可药用盐形式。本发明涉及这些抑制剂在减轻症状和治疗急性和慢性神经系统疾病,认知和神经变性疾病中的用途。

著录项

  • 公开/公告号EP3426634B1

    专利类型

  • 公开/公告日2020-01-22

    原文格式PDF

  • 申请/专利权人 UNIVERSITY OF LJUBLJANA;

    申请/专利号EP20170771757

  • 发明设计人 KNEZ DAMIJAN;SOVA MATEJ;GOBEC STANISLAV;

    申请日2017-09-22

  • 分类号C07D211/14;C07D211/18;C07D211/22;C07D211/34;A61K31/445;A61P25/16;A61P25/28;

  • 国家 EP

  • 入库时间 2022-08-21 11:40:30

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