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A PROCESS FOR MANUFACTURING POROUS SILICA PARTICLES LOADED WITH AT LEAST ONE BIOACTIVE COMPOUND ADAPTED FOR LUNG, NASAL, SUBLINGUAL AND/OR PHARYNGEAL DELIVERY
A PROCESS FOR MANUFACTURING POROUS SILICA PARTICLES LOADED WITH AT LEAST ONE BIOACTIVE COMPOUND ADAPTED FOR LUNG, NASAL, SUBLINGUAL AND/OR PHARYNGEAL DELIVERY
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机译:制造用于肺,鼻,舌下和/或咽部递送的至少具有一种生物活性化合物的多孔二氧化硅颗粒的制造方法
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摘要
The present invention relates to a process for manufacturing porous silica particles comprising at least one bioactive compound, whereby the particles are adapted for lung, nasal, sublingual and/or pharyngeal delivery of said at least one bioactive compound and have an MMAD between 0.5 and 15 μm with a GSD less than 2.5. The invention also relates to a pharmaceutical composition comprising said silica particles and a use of the silica particles in the diagnoses, prevention and/or treatment of local and/or systemic disorders, such as disorders of the lung, nose, sublingual and/or pharynx.
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