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COMPOUND FOR USE IN THE INCREASING OF MENTAL CAPABILITY

机译:用于提高心理能力的化合物

摘要

The invention relates to a compound, to the stereoisomers, enantiomers or diastereomers thereof, to the physiologically acceptable salts thereof and to mixtures of said compound for use in the increasing of mental capability. The invention further relates to a pharmaceutical composition. The increasing of mental capability is tested in learning experiments with Drosophila melanogaster larvae or older animals, which are raised with standard feed mash or with different concentrations of FSE-20 in the feed mash. In the learning experiment, the animals are each subjected to one of two inverse training regimens and then subjected to a test. In the training, a first scent (white square) was presented with the feed reward (fructose) (white circle with longitudinal stripes) to the first group, while a second scent (black square) was presented alone (white circle without the longitudinal stripes) to the first group. The second group was trained inversely. In the test of the learning experiment, it was subsequently examined whether the larvae of both groups prefer the first scent or the second scent in a selection situation, and thus their learning and memory capability (performance index) was determined.
机译:本发明涉及一种化合物,其立体异构体,对映异构体或非对映异构体,其生理上可接受的盐,以及所述化合物的混合物,其用于提高智力水平。本发明进一步涉及药物组合物。在用果蝇果蝇幼虫或年长动物进行的学习实验中测试了智力能力的提高,这些实验是用标准饲料或饲料mash中不同浓度的FSE-20饲养的。在学习实验中,对动物分别进行两种逆向训练方案之一,然后进行测试。在训练中,第一组的第一份气味(白色正方形)带有饲料奖励(果糖)(带有纵向条纹的白色圆圈),而第二组的气味(黑色正方形)则单独呈现(白色圆圈,没有纵向条纹) )到第一组。第二组训练相反。在学习实验的测试中,随后检查了在选择情况下两组幼虫是偏爱第一气味还是第二气味,从而确定了它们的学习和记忆能力(性能指标)。

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