首页> 外国专利> METHOD FOR PRODUCTION OF RECOMBINANT ERWINIA ASPARAGINASE

METHOD FOR PRODUCTION OF RECOMBINANT ERWINIA ASPARAGINASE

机译：重组ERWINIA天冬酰胺酶的生产方法

页面导航

摘要
著录项
相似文献

摘要

Provided herein are methods of production of recombinant Erwinia asparaginase. Methods herein produce asparaginase having high expression levels in the periplasm or the cytoplasm of the host cell having activity comparable to commercially available asparaginase preparations.

机译：本文提供了产生重组欧文氏菌天冬酰胺酶的方法。本文的方法产生在宿主细胞的周质或细胞质中具有高表达水平的天冬酰胺酶，其活性与可商购的天冬酰胺酶制剂相当。

著录项

公开/公告号EP3700921A1

专利类型
公开/公告日2020-09-02

原文格式PDF
申请/专利权人 PFENEX INC.;
展开▼

申请/专利号EP20180870766
发明设计人 COLEMAN RUSSELL J.;BRUCK TORBEN;
展开▼

申请日2018-10-17
分类号C07K14/535;C07K14/62;C07K14/635;
国家 EP
入库时间 2022-08-21 11:39:33

相似文献

专利
外文文献
中文文献

1. L-asparaginase production by mangrove derived Bacillus cereus MAB5:optimization by response surface methodology [J] . ThenmozhiC, SankarR, KaruppiahV, 亚太热带医药杂志（英文版） . 2011,第006期

2. Optimization of Fermentation Process for Human-like Collagen Production of Recombinant Escherichia coli Using Response Surface Methodology [J] . 张驰, 范代娣, 尚龙安, 中国化学工程学报：英文版 . 2010,第001期

3. Enhanced Production of Hybrid Extracellular β-Glucanase by Recombinant Escherichia coli Using Experimental Design Method [J] . 卢英华, 邓旭, 程志敬, 中国化学工程学报：英文版 . 2007,第002期

4. A　Novel　Method　for　Production　of　3-Hydroxydecanoic　Acid　by　Recombinant　Escherichia　coli　and　Pseudomonas　putida [J] . 郑重, 宫强, 陈国强中国化学工程学报：英文版 . 2004,第004期

5. PEGylated Recombinant L-Asparaginase from Erwinia carotovora: Production, Properties, and Potential Applications [J] . Applied biochemistry and microbiology . 2017,第2期

6. Recombinant Erwinia carotovora l-asparaginase II production in Escherichia coli fed-batch cultures [J] . C. P. Nunes, C. V. Bizarro, D. S. Santos, Brazilian journal of chemical engineering . 2013,第2期

7. Extracellular Production of Recombinant L-Asparaginase II in Escherichia coli: Medium Optimization Using Response Surface Methodology [J] . Ghoshoon, Mohammad Bagher, Berenjian, Aydin, Hemmati, Shiva, International journal of peptide research and therapeutics . 2015,第4期

8. Recombinant L-Asparaginase II - purification by crystallization [C] . C. Muller, A. Migge, M. Pietzsch, International Workshop on Industrial Crystallization . 2010

9. Baculovirus Production Methods For Reliable Isolation of Recombinant Baculovirus Engineered For Modified Actin Expression. [D] . Hayes, Brooks Christian. 2014

10. A Randomized Phase I Study to Evaluate the Safety Tolerability and Pharmacokinetics of Recombinant Erwinia Asparaginase (JZP‐458) in Healthy Adult Volunteers [O] . Tong Lin, Martha Hernandez‐Illas, Andres Rey, 2021

11. Recombinant Erwinia carotovora l-asparaginase II production in Escherichia coli fed-batch cultures [O] . G. Roth, J. E. S. Nunes, L. A. Rosado, 2013

12. Production of L-Asparaginase by Cultures of Erwinia Aroideae. [R] . murphy, t. . wilke, c. . 1973

1. Batch, Fed Batch Production and Characterization of Glutaminase Free L-Asparaginase II of iPectobacterium carotovorum/iMTCC 1428 in iEscherichia coli/i [J] . Rachna Goswami ,Krishnamoorthy Hegde ,Venkata Dasu Veeranki . 微生物学（英文） . 2014,第10期

2. 链霉菌sp.139编码糖基转移酶的Ste7基因和编码天冬酰胺合成酶Ste10基因在依博素生物合成中的功能研究 [C] . 白利平 ,李元 . 第五届中国酶工程学术研讨会 . 2005

3. 基于订单重组的大规模定制生产方法研究 [A] . 李伟欣 . 2006