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CHIRAL DIARYL MACROCYCLE AND USE THEREOF IN THE TREATMENT OF CANCER
CHIRAL DIARYL MACROCYCLE AND USE THEREOF IN THE TREATMENT OF CANCER
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机译:手性二尖瓣大环化合物及其在癌症治疗中的应用
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摘要
This disclosure relates to the use of certain diaryl macrocycle compounds, specifically (7S,13R)-11-fluoro-7,13-dimethyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4(5H)-one in the treatment of disease in mammals. This disclosure also relates to compositions including such compounds, and to methods of using such compositions in the treatment of diseases in mammals, especially in humans.
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机译:本公开涉及某些二芳基大环化合物的用途,特别是(7 I,13 R I>)-11-氟-7,13-二甲基-6,7,13 ,14-tetrahydro-1,15-ethenopyrazolo [4,3- f I>] [1,4,8,10] benzoxatriazazacyclotridecin-4(5 H I>)-哺乳动物疾病的治疗。本公开内容还涉及包含此类化合物的组合物,以及使用此类组合物治疗哺乳动物,尤其是人类疾病的方法。
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