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METHOD FOR TREATING CANCER WITH A COXSACKIEVIRUS B3 (CVB3) VARIANT
METHOD FOR TREATING CANCER WITH A COXSACKIEVIRUS B3 (CVB3) VARIANT
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机译:柯萨奇病毒B3(CVB3)变异治疗癌症的方法
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摘要
The present invention relates to a method for treating cancer in a subject in need thereof, comprising administering to said subject a therapeutically effective amount of a Coxsackie B3 group virus or a modified form thereof, wherein the cells of the cancer express a heparan sulfate (HS) receptor on their surface and the virus binds to said HS receptor, enters and accumulates in the cancer cells, whereby at least some cancer cells undergo viral lysis.
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