TIM PROTEIN-BOUND CARRIER, METHODS FOR OBTAINING, REMOVING AND DETECTING EXTRACELLULAR MEMBRANE VESICLES AND VIRUSES USING SAID CARRIER, AND KIT INCLUDING SAID CARRIER

摘要

An object of the present invention is to provide a carrier and a method for obtaining or removing extracellular membrane vesicle or virus present in a sample in good purity and in an intact state simply and conveniently, as well as and efficiently, or detecting them in high sensitivity.;The present invention relates to: "1. a carrier (a Tim carrier) on which a protein (a Tim protein), selected from a T-cell immunoglobulin and mucin domain-containing molecule-4 (a Tim-4) protein, a Tim-3 protein, and a Tim-1 protein, is bound; 2. a method for obtaining the extracellular membrane vesicle or the virus in the sample; 3. a method for removing the extracellular membrane vesicle or the virus in the sample; 4. a method for detecting the extracellular membrane vesicle or the virus in the sample; 5. a kit for capturing the extracellular membrane vesicle or the virus, comprising the Tim carrier; and 6. a kit for capturing the extracellular membrane vesicle or the virus, comprising a reagent containing the Tim protein and a reagent containing the carrier".