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TISSUE-DERIVED EXTRACELLULAR VESICLES AND THEIR USE AS DIAGNOSTICS
TISSUE-DERIVED EXTRACELLULAR VESICLES AND THEIR USE AS DIAGNOSTICS
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机译:组织来源的细胞外囊膜及其作为诊断的用途
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摘要
The present disclosure relates to a method of isolating extracellular vesicles directly from human tissues. The invention further relates to a method of identifying disease and tissue specific membrane proteins on extracellular vesicles by membrane isolation and proteomic analysis. The invention further relates to methods of diagnosing diseases by capturing extracellular vesicles by the use of disease specific membrane proteins from body fluids, and detecting or analyzing molecular signatures (proteome, DNA, and RNA) on captured extracellular vesicles. Moreover, the present invention relates to kits, apparatus and software required for implementing aforementioned methods.
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