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MOLECULAR SUBTYPING, PROGNOSIS, AND TREATMENT OF BLADDER CANCER
MOLECULAR SUBTYPING, PROGNOSIS, AND TREATMENT OF BLADDER CANCER
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机译:膀胱癌的分子分型,预后和治疗
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摘要
The present invention relates to methods, systems and kits for the diagnosis, prognosis, and treatment of bladder cancer in a subject. The invention also provides biomarkers that define subgroups of bladder cancer, clinically useful classifiers for distinguishing bladder cancer subtypes, bioinformatic methods for determining clinically useful classifiers, and methods of use of each of the foregoing. The methods, systems and kits can provide expression-based analysis of biomarkers for purposes of subtyping bladder cancer in a subject. Further disclosed herein, in certain instances, are probe sets for use in subtyping bladder cancer in a subject. Classifiers for subtyping a bladder cancer are provided. Methods of treating bladder cancer based on molecular subtyping are also provided.
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