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Co-administration of internalized peptide-linked drug and anti-inflammatory drug

机译:内化肽连接药物和抗炎药的共同给药

摘要

Provided is a drug for inhibiting cerebral ischemia caused by endovascular surgery. SOLUTION: An endogenous drug that inhibits the binding of post-synaptic thickened part-95 protein (PSD-95) to NMDAR2B, which is used in combination with a mast cell degranulation inhibitor that blocks an internalized peptide-induced inflammatory response Peptide-linked pharmacological agent. Preferably, the mast cell degranulation inhibitor is rhodoxamide. [Selection diagram] Fig. 15
机译:提供了抑制血管内手术引起的脑缺血的药物。解决方案:一种内源性药物,可抑制突触后加厚的part-95蛋白(PSD-95)与NMDAR2B的结合,该药物与肥大细胞脱粒抑制剂联合使用,可阻止内在的肽诱导的炎症反应肽联的药理作用代理商。优选地,肥大细胞脱粒抑制剂是rhodoxamide。 [选择图]图15

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