Prevention and treatment of metastatic disease in patients with thrombocytopenic cancer

摘要

PROBLEM TO BE SOLVED: To provide a compound and a pharmaceutical composition for prevention and / or treatment of metastatic disease in a cancer patient showing paraneoplastic thrombocytosis. An anagrelide, a pharmaceutically acceptable salt of anagrelide, a solvent mixture of anagrelide, or an active metastasis of anagliredo, wherein the active metastasis of anagliredo is alone or in combination at positions 5, 8 or 9. For the treatment or prevention of metastatic disease in patients with thrombocytopenic cancer who are hydroxylated and / or are oxidized at the position of tertiary nitrogen to form N-oxide. The cancers used and treated are: brain, oral, head and neck, thyroid cancer, gastrointestinal cancer, pancreatic, hepatocellular carcinoma, conjunctival cancer, lung and bronchial cancer, ovarian cancer, intrauterine. A compound selected from the group consisting of membrane, cervical, breast, prostate, kidney, cutaneous dermatoma, melanoma, bile sac and multiple myeloma. [Selection diagram] None