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Functional sequence selection method and functional sequence selection system

机译:功能序列选择方法及功能序列选择系统

摘要

PROBLEM TO BE SOLVED: To provide a novel functional sequence selection method and a functional sequence selection system. SOLUTION: This is a method for selecting a functional sequence for producing a recombinant gene for expressing a gene in a cell, and in a database, a base sequence of a coding region of a target gene, a base sequence encoding an amino acid sequence, or a base sequence. A step of searching for a base sequence having homology using an amino acid sequence, and extracting a base sequence other than the base sequence whose entire body is derived from the genome from the obtained base sequence, and (1) using the extracted base sequence On the other hand, if there is a base sequence upstream or downstream, it is analyzed whether it is a functional sequence and the first functional sequence is extracted. (2) If it does not exist, the description indicating the functional sequence is shown in the description of the gene information. A step of searching for the presence of a second functional sequence and extracting a second functional sequence, a step of scoring the obtained functional sequence, and a step of selecting a higher functional sequence as a result of scoring. And, the functional sequence selection method including. [Selection diagram] Fig. 1
机译:要解决的问题:提供一种新颖的功能序列选择方法和功能序列选择系统。 SOLUTION:这是一种选择功能序列的方法,该功能序列用于产生可在细胞中表达该基因的重组基因,并在数据库中选择靶基因编码区的碱基序列,编码氨基酸序列的碱基序列,或基本序列。步骤是使用氨基酸序列搜索具有同源性的碱基序列,并从获得的碱基序列中提取除其整体来源于基因组的碱基序列以外的碱基序列,以及(1)使用提取的碱基序列On。另一方面,如果在上游或下游存在碱基序列,则分析其是否为功能序列并提取第一功能序列。 (2)如果不存在,则在基因信息的描述中显示指示功能序列的描述。搜索第二功能序列的存在并提取第二功能序列的步骤,对获得的功能序列进行评分的步骤以及作为评分结果选择较高功能序列的步骤。并且,功能序列选择方法包括。 [选择图]图1

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