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Antibacterial or antifungal peptides and antibacterial or antifungal agents

机译:抗菌或抗真菌肽和抗菌或抗真菌剂

摘要

PROBLEM TO BE SOLVED: To provide a low molecular weight peptide having strong antibacterial or antifungal activity independent of salt concentration and having extremely low toxicity to eukaryotic cells, and an antibacterial or antifungal drug using the same. SOLUTION: The following peptides (a), (b) or (c), derivatives thereof or salts thereof. (a) A peptide containing a specific amino acid sequence. (b) A peptide containing an amino acid sequence in which one or several amino acids are deleted, substituted, or added in a specific amino acid sequence, and which has antibacterial or antifungal activity. (c) A peptide containing an amino acid sequence having 80% or more identity with a specific amino acid sequence and having antibacterial or antifungal activity. [Selection diagram] None
机译:解决的问题:提供一种低分子量肽,其具有与盐浓度无关的强抗菌或抗真菌活性,并且对真核细胞具有极低的毒性,并提供了使用该低分子量肽的抗菌或抗真菌药物。解决方案:以下肽(a),(b)或(c),其衍生物或其盐。 (a)含有特定氨基酸序列的肽。 (b)一种含有氨基酸序列的肽,该肽具有在特定氨基酸序列中缺失,取代或添加的一个或几个氨基酸,并且具有抗菌或抗真菌活性。 (c)一种肽,其含有与特定氨基酸序列具有80%或更高的同一性并且具有抗菌或抗真菌活性的氨基酸序列。 [选择图]无

著录项

  • 公开/公告号JP2020152640A

    专利类型

  • 公开/公告日2020-09-24

    原文格式PDF

  • 申请/专利权人 学校法人獨協学園獨協医科大学;

    申请/专利号JP20170130369

  • 发明设计人 大塚 裕一;増田 道明;

    申请日2017-07-03

  • 分类号C07K7/06;C07K5/10;A61P31/04;A61P31/10;A61K38/07;A61K38/08;C07K5/103;

  • 国家 JP

  • 入库时间 2022-08-21 11:37:16

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