SAFETY EVALUATION METHOD FOR ALPHA-RAY NUCLEAR MEDICINE TREATMENT AGENT AND SCREENING METHOD

摘要

To provide a safety evaluation technique for an alpha-ray nuclear medicine treatment agent, a screening method, and a translational research method shifting from a non-clinical stage to a clinical stage for an alpha-ray nuclear medicine treatment agent using these methods.SOLUTION: A non-clinical safety evaluation method includes conducting a hematological examination, a blood biochemical examination, and a histopathological examination, at a first time point and a second time point after administration of an alpha-ray nuclear medicine treatment agent using astatine 211 and actinium 225 as alpha-ray emitting nuclides.SELECTED DRAWING: None