Methods for treating focal segmental glomerulosclerosis

摘要

Provided are methods of treating focal segmental glomerulosclerosis using a compound of Formula I. FSGS can be primary (the cause is not clear) or secondary. Secondary FSGS includes infection or diseases such as HIV, sickle cell disease or lupus, toxins or drugs such as anabolic steroids, heroin or pamidronate, nephron loss, and hyperfiltration with chronic pyelonephritis and reflux, etc. It may be associated with morbid obesity or diabetes. [Selection diagram] Fig. 1