PREPARATION METHOD FOR ANALYSIS SAMPLE, ANALYSIS METHOD, AND KIT FOR ANALYSIS SAMPLE PREPARATION

摘要

PROBLEM TO BE SOLVED: To provide a preparation method for analysis samples that involves more accurately modifying coupling scheme specific sialic acid.;SOLUTION: Provided is a preparation method for analysis samples for analyzing the sugar chain contained in a sample, the method including: when sialic acid is bound to the sugar chain, carrying out a first reaction for performing lactonization for sialic acid of a first coupling scheme and performing modification, different from lactonization, for sialic acid of a second coupling scheme different from the first coupling scheme; carrying out a second reaction to open the ring of lactone generated in the first reaction; and carrying out the first reaction again.;SELECTED DRAWING: Figure 2;COPYRIGHT: (C)2020,JPO&INPIT