Multi-domain capsule containing immunosuppressive factor controlling substance, method for producing the same, and immunomodulating composition containing the same

摘要

The present invention provides a multi-domain capsule containing an immunosuppressive factor controlling substance, a method for producing the multi-domain capsule, and an immunomodulatory composition containing the multi-domain capsule. According to one aspect of the present invention, there is provided a multi-domain capsule comprising two or more liposomes in contact with and linked to each other, and a multi-domain capsule outer wall surrounding the two or more liposomes, The multi-domain capsule comprises an organic phase and an aqueous phase, wherein the organic phase includes a first immunomodulator and a fluid oil, and the organic phase forms a membrane of the liposome and an outer wall of the multi-domain capsule. The aqueous phase includes a second immunomodulator, and the aqueous phase is an internal aqueous phase of the liposome membrane and an external aqueous phase of the liposome membrane, and the first immunomodulator and the second immunomodulator. The modulator is an immunosuppressive factor regulator, wherein the fluid oil comprises two or more liposomes in contact with and linked to each other. Characterized in that for improving the forming stability, multidomain capsule may be provided. [Selection diagram] Fig. 1