Platform for identification of individualized immunogenic peptides

摘要

The present disclosure provides methods for identifying fragments of a polypeptide that are immunogenic to a particular human subject, methods of preparing an individualized pharmaceutical composition comprising such a polypeptide fragment, human subjects comprising such a polypeptide fragment. To specific pharmaceutical compositions and methods of treatment using such compositions. The method involves the identification of fragments of the polypeptide that bind to multiple HLAs in the subject. [Selection diagram] None