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Fatty acid synthase inhibitors for use in the treatment of drug resistant cancer
Fatty acid synthase inhibitors for use in the treatment of drug resistant cancer
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机译:脂肪酸合酶抑制剂用于抗药性癌症的治疗
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摘要
Compounds that are fatty acid synthesis modulators are provided. The compounds may be used in pharmaceutical compositions to treat taxane-resistant cancers. Methods are provided for treating taxane-resistant cancer in a subject. Methods are also provided for increasing the sensitivity of a cancer cell to taxanes (i.e., paclitaxel, Nab-paclitaxel docetaxel, and/or cabazitaxel) treatment.
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