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Method for screening blood IgA production inhibitor or preventive or therapeutic agent for diseases caused by excessive IgA in blood

机译:筛选血液中IgA产生抑制剂或预防或治疗剂的方法,用于预防血液中过量IgA引起的疾病

摘要

A screening method suitable for screening for a blood IgA production inhibitor, a blood IgA production promoter, or a preventive or therapeutic agent for a disease caused by excess blood IgA, a blood IgA production inhibitor, and a blood IgA production promoter A method suitable for controlling the amount of IgA in the blood and a method for assessing the risk, degree or condition of the disease caused by excess IgA in the blood, and removal for preventing or treating the disease caused by excess IgA in the blood Provided is a method for presenting at least one selected from the group consisting of enterobacteria to be administered and enterobacteria to be administered. Inhibition of expression of antibacterial protein gene of intestinal innate immunity system, promotion of expression or activity of said antibacterial protein, or increase in reaction of said antibacterial protein as an index For screening for preventive or therapeutic agents for diseases caused by the disease.
机译:适用于筛选血液IgA产生抑制剂,血液IgA产生促进剂或由过量血液IgA引起的疾病的预防或治疗剂的筛选方法,血液IgA产生抑制剂和血液IgA产生促进剂控制血液中IgA的量以及评估血液中过量IgA引起的疾病的风险,程度或状况的方法,以及用于预防或治疗血液中过量IgA引起的疾病的清除方法呈现至少一种选自待施用的肠细菌和待施用的肠细菌的组。肠固有免疫系统的抗菌蛋白基因的表达的抑制,所述抗菌蛋白的表达或活性的提高或所述抗菌蛋白的反应的增加作为用于筛选由疾病引起的疾病的预防剂或治疗剂的指标。

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