NR2B n-alkylol Lille - 5 - oxyaryl - octahydro cyclopenta C pyrronegative negative allosteric modulators

摘要

PROBLEM TO BE SOLVED: To provide pharmaceutical compositions useful in treating a neurological disease, an abnormal brain function, and/or an emotional disorder such as bipolar disorder, obsessive-compulsive disorder, post-traumatic stress syndrome, or anxiety, by modulating NR2B receptors.;SOLUTION: For example, the compositions comprise compounds having an N-alkylaryl-5-oxyaryl-octahydro-cyclopenta[c]pyrrole structure represented by the formula in the figure.;SELECTED DRAWING: None;COPYRIGHT: (C)2019,JPO&INPIT