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Fused cyclic pyrimidine compounds as dual inhibitors of BRAD4 and JAK2 and methods for their use
Fused cyclic pyrimidine compounds as dual inhibitors of BRAD4 and JAK2 and methods for their use
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机译:融合的环状嘧啶化合物作为BRAD4和JAK2的双重抑制剂及其使用方法
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摘要
The present invention relates to fused cyclic pyrimidine compounds, in particular pyrrolopyrimidine and thienopyrimidine compounds and derivatives thereof, pharmaceutical compositions thereof, methods of inhibiting BRAD4 and / or JAK2, and various compounds such as cancer and leukemia. Methods for treating diseases and conditions. Includes bromodomain binding and JAK activity. [Selection diagram] None
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