Lung cancer diagnosis method by bacterial metagenome analysis

摘要

The present invention relates to a method for diagnosing lung cancer by bacterial metagenomic analysis, and more particularly to diagnosing lung cancer by analyzing bacterial metagenome analysis using a sample derived from a subject to analyze the increase or decrease in the content of specific bacterial-derived extracellular vesicles About the method. Extracellular vesicles secreted by bacteria present in the environment can be absorbed into the body and have a direct effect on cancer development, and lung cancer is difficult to diagnose early before symptoms appear and it is difficult to treat it efficiently Early diagnosis and prediction of lung cancer risk group by predicting in advance the risk of developing lung cancer by metagenomic analysis for genes present in bacterial-derived extracellular vesicles using a human-derived sample according to the present invention It is possible to delay the onset of the disease or prevent the onset of the disease through appropriate management, and to diagnose the disease early after the onset of the disease, thereby reducing the incidence of lung cancer and increasing the therapeutic effect. [Selection diagram] FIG.