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Method for distinguishing tumor suppressive FOXO activity from oxidative stress

机译:区分肿瘤抑制性FOXO活性与氧化应激的方法

摘要

The present invention relates to specific target genes of the FOXO transcription factor family that are markers for oxidative stress states and can be used to infer the oxidative stress state of FOXO transcription factor elements in the body of a medical subject. The present invention further relates to a method for estimating an oxidative stress state of a FOXO transcription element and a method for estimating an activity of a FOXO / PI3K cell signaling pathway based on a target gene expression level and a product for performing the method.
机译:本发明涉及FOXO转录因子家族的特定靶基因,其是氧化应激状态的标记,并且可用于推断医学对象体内FOXO转录因子元件的氧化应激状态。本发明还涉及一种基于目标基因表达水平的FOXO转录元件的氧化应激状态的估计方法和FOXO / PI3K细胞信号通路的活性的估计方法以及用于执行该方法的产物。

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