PROBLEM TO BE SOLVED: To provide a preparation method of a sample capable of analyzing an advanced glycation end product (AGE) derived from an organism of an educt, highly sensitively, highly accurately and comprehensively.SOLUTION: A filtration treatment by an ultrafilter membrane and a reduction treatment are applied. A cutoff molecular weight of the ultrafilter membrane is preferably 10,000, and more preferably 3,000. Further, a refining treatment by a strong acid cation-exchange resin is preferably applied to a sample to which the filtration treatment by the ultrafilter membrane and the reduction treatment are applied.SELECTED DRAWING: None
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