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Pathophysiology biomarkers of kidney disease

机译:肾脏疾病的病理生理生物标志物

摘要

The present invention addresses the problem of developing an analytical method which makes it possible to diagnose early or mild renal disorders. The method is based on calculating a disease-state index value for renal disorders on the basis of the quantities of D-form and/or L-form amino acids, from feces or intestinal content. By comparing the disease-state index value with a threshold value determined from the disease-state index values of a renal failure patient group and a healthy subject group, it is possible to diagnose a mild renal disorder patient group.
机译:本发明解决了开发分析方法的问题,该分析方法使得诊断早期或轻度肾脏疾病成为可能。该方法基于从粪便或肠内容物基于D-形式和/或L-形式氨基酸的量计算肾疾病的疾病状态指数值。通过将疾病状态指标值与根据肾衰竭患者组和健康受试者组的疾病状态指标值确定的阈值进行比较,可以诊断轻度肾病患者组。

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