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Method for Producing a Stable Low Concentration Injectable Solution of Noradrenaline
Method for Producing a Stable Low Concentration Injectable Solution of Noradrenaline
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机译:一种去甲肾上腺素稳定低浓度注射液的制备方法
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摘要
In a first aspect, the present invention relates to a process for producing a stable, injectable solution with low content of noradrenaline, which includes dissolving noradrenaline and optionally an excipient in deoxygenated or degassed water, filtrating the resulting noradrenaline solution in a nitrogen current, distributing the solution in a nitrogen current, and sterilization, preferably hot. The invention further provides a stable, injectable solution with low content of noradrenaline, substantially free of anti-oxidizing and preservative agents, as well as uses thereof in the medical and pharmaceutical fields.
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