首页>
外国专利>
Methods, compounds and methods for synthesizing cycloalkanyl b indole, cycloalkanyl b benzofuran, cycloalkanyl b benzothiophene
Methods, compounds and methods for synthesizing cycloalkanyl b indole, cycloalkanyl b benzofuran, cycloalkanyl b benzothiophene
展开▼
机译:合成环烷基[b]吲哚,环烷基[b]苯并呋喃,环烷基[b]苯并噻吩的方法,化合物和方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method of synthesizing cycloalkanyl[b]indoles, as well as related cycloalkanyl[b]benzofurans and cycloalkanyl[b]benzothiophenes is provided. The method is a single, multicomponent reaction that combines (1) an indole, benzofuran, or benzothiopene, (2) an aldehyde, ketone, or ketal, and (3) a diene in the presence of an acid, in particular a Ga(III) or In(III) salt. Compositions and methods of using these compounds to stimulate secretion and/or production of glucagon-like peptide-1 or inhibit the activity of Calcitonin Gene-Related Peptide receptor are also provided.
展开▼