Therapeutic agent for cancer and precancerous lesion, treatment method, and method for producing therapeutic agent

摘要

The invention describes compositions and methods of use for pyrithione compounds and pharmacologically acceptable salts thereof. The invention provides topical administration methods for treating skin cancers, treating cervical cancer, treating other cancers, preventing skin cancer development from precancerous skin conditions, preventing cervical cancer development from chronic human papillomavirus (HPV) infection, preventing development of other cancers from chronic HPV infection. Also disclosed are compositions comprising at least one pyrithione compound, ethylenediaminetetraacetic acid (EDTA), ascorbic acid, any salt and chemical derivatives thereof, pyridoxine and any derivative thereof and pharmacologically acceptable buffers. In these compositions, pH of the compositions is adjusted to between 4.5 and 6.4.