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METHOD FOR SUPPORTING DIAGNOSIS OF THREE MAJOR NEURODEGENERATIVE DISEASES

机译:支持三项主要神经退行性疾病诊断的方法

摘要

To provide a method for supporting diagnosis to rapidly determine whether a subject is affected with any of at least three major neurodegenerative diseases.SOLUTION: The method for supporting diagnosis of the three major neurodegenerative diseases of Alzheimer disease, Parkinson disease, and ALS according to the present invention includes: obtaining the mass spectrum of a sample collected from a subject by MALDI/TOF-MS; and determining whether the result for the subject is positive or negative for the three major neurodegenerative diseases on the basis of the respective peak values of the mass-to-charge ratio (m/z) of the thus obtained mass spectrum at m/z1733±1 and m/z2399±1 or the level of a predetermined peak information value derived from the peak values.SELECTED DRAWING: None
机译:提供一种支持诊断的方法,以快速确定受试者是否患有至少三种主要神经退行性疾病。本发明包括:通过MALDI / TOF-MS获得从受试者收集的样品的质谱。根据所得到的质谱的质荷比(m / z)的各自的峰值,以m / z1733±为基准,判别三种主要神经退行性疾病的结果为阳性还是阴性。 1和m / z2399±1或从峰值中得出的预定峰值信息值的水平。

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