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Inhibitors of beta integrin-G protein alpha subunit binding interactions
Inhibitors of beta integrin-G protein alpha subunit binding interactions
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机译:β整联蛋白-G蛋白α亚基结合相互作用的抑制剂
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摘要
Provided herein are compounds that inhibit a binding interaction between a β integrin and a G protein subunit, as well as compositions, e.g., pharmaceutical compositions, comprising the same, and related kits. In some embodiments, the compound is an antibody or antibody analog, and, in other embodiments, the compound is a peptide or peptide analog. Also provided are methods of using the compounds, including methods of treating or preventing a medical condition, such as stroke, heart attack, cancer, or inflammation.
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