Triazole derivatives as P2Y₁₄ receptor antagonists

摘要

Described are compounds, which are antagonists of the P2Y₁₄ receptor, for example, a compound of formula (I) in which ring A, R¹, R², R³, and n are as described herein. Also provided are dendron conjugates comprising the compounds, and methods of using the compounds, including a method of treating a disorder, such as inflammation, diabetes, insulin resistance, hyperglycemia, a lipid disorder, obesity, a condition associated with metabolic syndrome, and asthma, and a method of antagonizing P2₁₄ receptor activity in a cell.;