System and method for separation of water and fat signals during spin-lock magnetic resonance imaging

摘要

Separation of fat and water signals in MRI images can be achieved by a technique that includes using a spin-lock RF pulse sequence that incorporates adiabatic pulses and using Dixon methods for water/fat separation. The spin-lock RF pulse sequence can be, for example, an adiabatic continuous-wave constant-amplitude spin-lock (ACCSL) pulse sequence. Data acquisition can use any acquisition method compatible with Dixon methods. Following data acquisition, a source image can be generated and analyzed (e.g., using Dixon methods) to generate separate water and fat images. A spatial distribution of a spin-lock based imaging biomarker (e.g., T1rho) can be determined from the water image and/or the fat image.