首页> 外国专利> Methods for treating subjects having a CXC chemokine receptor 5 (CXCR5)-responsive cancer by administering fully human anti-CXCR5 antibodies

Methods for treating subjects having a CXC chemokine receptor 5 (CXCR5)-responsive cancer by administering fully human anti-CXCR5 antibodies

机译:通过施用完全人抗CXCR5抗体治疗具有CXC趋化因子受体5(CXCR5)反应性癌症的受试者的方法

摘要

There is disclosed compositions and methods relating to or derived from anti-CXCR5 antibodies. More specifically, there is disclosed fully human antibodies that bind CXCR5, CXCR5-binding fragments and derivatives of such antibodies, and CXCR5-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having CXCR5 related disorders or conditions, including various inflammatory disorders and various cancers.
机译:公开了涉及或衍生自抗CXCR5抗体的组合物和方法。更具体地,公开了结合CXCR5,CXCR5结合片段和此类抗体的衍生物的完全人抗体,以及包含此类片段的CXCR5结合多肽。更进一步,公开了编码此类抗体,抗体片段和衍生物和多肽的核酸,包含此类多核苷酸的细胞,制备此类抗体,抗体片段和衍生物和多肽的方法以及使用此类抗体,抗体片段和衍生物和多肽的方法。包括治疗或诊断患有CXCR5相关疾病或病症(包括各种炎症性疾病和各种癌症)的受试者的方法。

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