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Microorganism having improved ability to produce N-acetylglucosamine as a result of modulating glycolytic flux
Microorganism having improved ability to produce N-acetylglucosamine as a result of modulating glycolytic flux
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机译:由于调节糖酵解通量,具有提高的生产N-乙酰氨基葡萄糖能力的微生物
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摘要
The present invention relates to a mutant microorganism in which a gene that encodes phosphofructokinase-2 is disrupted or deleted to reduce glycolytic flux to thereby improve the ability of the microorganism to produce N-acetylglucosamine, and to a method of producing N-acetylglucosamine using the mutant microorganism. The mutant microorganism according to the present invention has advantages in that it has high resistance to various chemical substances, grows rapidly, is easily cultured, and produces N-acetylglucosamine with high efficiency, indicating that it is useful for production of a large amount of N-acetylglucosamine.
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